FAS-L Polyclonal Antibody
簡要描述:FAS-L Polyclonal Antibody宿主: Polyclonal, Rabbit,IgG反應性: Human;Rat;Mouse;應用: IHC;IF;ELISA
產(chǎn)品型號: YP-Ab-00590
所屬分類:多克隆抗體
更新時間:2024-10-31
詳細說明:
FAS-L Polyclonal Antibody
抗體,也叫免疫球蛋白(Ig),是一種能特異性結(jié)合抗原的糖蛋白,而抗原是在易感染動物體內(nèi)引發(fā)抗體產(chǎn)生的物質(zhì)。在體內(nèi),抗體是由于外源性分子的侵襲而產(chǎn)生的??贵w以一個或者多個Y字形單體存在,每個Y字形單體由4條多肽鏈組成,包含兩條相同的重鏈和兩條相同的輕鏈。輕鏈和重鏈是根據(jù)它們的分子量大小來命名的。Y字形結(jié)構的頂端是可變區(qū),為抗原結(jié)合部位。任何一個抗體的輕鏈都可以分為κ或λ型(基于小分子多肽結(jié)構上的差異),每一個抗體的重鏈則決定了它的類或型。
保存溫度:-20℃
產(chǎn)品詳情
免疫原詳細信息
Synthetic peptide from human protein at AA range: 121-170
相關試劑
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
背景
This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014]。
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備注:圖片僅供參考。僅供科研,不可用于臨床。